Sunday, March 11, 2018

Case report of Successful Pregnancy of a 44 year old lady after 10 year trials and 10 Failed IVFs

successful pregnancy with ivf case report
"A 44 year old lady visited our fertility center with her 52 year old husband with 10 year infertility medical record at September 2016. The lady was submitted in laparoscopic surgery for endometriosis at 2007, and at 2010 she performed laparoscopic surgery and removed the right salpinx and a year later the left one was removed respectively.

The couple has started attempts for a baby since 2008 and they had their IVFs from 2011 until May 2016, and they never had a successful pregnancy. So, they heard about our center and wanted to exhaust their last chance so they would not let down their dream to have a baby.

Their next step according to our guidance was to do our specific individualized immune tests. The lady was tested for NK panel (total, endometrial NK cells, and their activity), where the endometrial NK number was too high. Also, Platelet-leucocyte-aggregates (PLA) test was performed and this marker was high too. We explained the couple that NK was the major reason for their failed implantation, and we planned therapeutic strategy in order to regulate the NK cells and go to next IVF trial with much higher chances for successful pregnancy. On the other hand, Husband’s sperm analysis and DNA fragmentation were fine, while the levels of Vitamin D3 of the lady were low and we administered supplement of Vitamin D3 and baby aspirin.

Based on the diagnostic result, 2 dosages of intralipid were administered before the embryo transfer in order to regulate suitably the NK cells for the next IVF trial. Then, the process of embryo transfer of 2 embryos followed and after 10 days a positive pregnancy test was detected for the FIRST TIME after so many years. Then a final dosage of intralipid was administered, so the danger of miscarriage can be limited down at the first trimester of gestation. At the first UV one embryo was detected with positive heart beats and pulses, and the couple was very happy. Later, The Nuchar translucency screening was followed and level 2 ultrasound by Dr. Spyros Papageorgiou and the pregnancy continued normally without any problems. The baby was born at November 2017 with 3100gr weight and the couple was very happy after all these 10 years of trials..."

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