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| credit: checkpregnancy.com |
"New research suggests that following a high-fat diet during lactation—regardless of diet during pregnancy—alters RNA activity in breast milk. The changes in genetic material may increase the risk of metabolic disorders such as type 2 diabetes in offspring. The article is published ahead of print in Physiological Genomics.
RNA is a molecule chain that uses genetic information from DNA—the "genetic blueprint"—to produce proteins in the cells. RNA defects can play a role in potentially serious health conditions such as cancer, heart disease and stroke.
Previous studies have shown that offspring born to mothers who consumed a high-fat diet during pregnancy and breastfeeding are more likely to become obese and develop chronic conditions such as diabetes, high blood pressure and heart disease. However, less is known about the effects of a high-fat diet during lactation alone.
Researchers from Purdue University in Indiana studied two groups of pregnant mice. One group was given a high-fat diet during gestation and the other was fed a typical diet. The research team divided the newborn mice pups into four groups:
RNA is a molecule chain that uses genetic information from DNA—the "genetic blueprint"—to produce proteins in the cells. RNA defects can play a role in potentially serious health conditions such as cancer, heart disease and stroke.
Previous studies have shown that offspring born to mothers who consumed a high-fat diet during pregnancy and breastfeeding are more likely to become obese and develop chronic conditions such as diabetes, high blood pressure and heart disease. However, less is known about the effects of a high-fat diet during lactation alone.
Researchers from Purdue University in Indiana studied two groups of pregnant mice. One group was given a high-fat diet during gestation and the other was fed a typical diet. The research team divided the newborn mice pups into four groups:
- born to and fed by mothers that followed a high-fat diet;
- born to mothers that followed a high-fat diet and fed by mothers that followed a typical diet;
- born to typical-diet mothers and fed by high-fat-diet mothers; and
- born to and fed by normal-diet mothers..."
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