via bio100.class.uic.edu |
"A ground-breaking study by University of Manchester and Liverpool scientists and published in the journal eLife has identified a new link between inflammation and cell division.
Two of the most important processes in the human body, their accurate control is a holy grail for scientists researching the prevention of infection, inflammatory disease and cancer.
Professor Mike White, who led the BBSRC-funded research and investigates how cells adapt to signals in the body, hit upon the discovery using advanced microscopy and mathematical modelling at The University of Manchester's world-leading systems microscopy centre and the University of Liverpool's Centre for Cell Imaging.
"This is an exciting discovery: for the first time we find a link between the system which regulates how cells divide and the basis of some of medicine's most intractable diseases," he said.
Inflammatory signals produced by a wound or during an infection can activate a protein called Nuclear Factor-kappaB (NF-κB), which controls the activity of genes that allow cells to adapt to the situation..."
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