Source: BioMed Central | Summary: Infertility and hormonal fertility treatments may influence the amount of dense tissue in the breast, a risk factor for breast cancer, according to a study involving 43,313 women.
"Infertility and hormonal fertility treatments may influence the amount of dense tissue in the breast, a risk factor for breast cancer, according to a study involving 43,313 women, published in the open access journal Breast Cancer Research.
Researchers at Karolinska Institutet, Sweden found that women with a history of infertility had denser breasts than other women. The association was more pronounced in women who had undergone controlled ovarian stimulation (COS), the hormone treatment required for in vitro fertilization.
While this may indicate a potential adverse effect of COS on breast density, the researchers point out that the effect may be due to the underlying infertility that motivates the use of a specific treatment, rather than to the treatment itself.
Frida Lundberg, lead author of the study, said: "The results from our study indicate that infertile women, especially those who undergo COS, might represent a group with an increased breast cancer risk. While we believe it is important to continue monitoring these women, the observed difference in breast tissue volume is relatively small and has only been linked to a modest increase in breast cancer risk in previous studies..."
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