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| via thesun.co.uk |
"Women undergoing in vitro fertilization (IVF) may become pregnant with fewer treatment cycles, thanks to a new device developed by a team of researchers from Worcester Polytechnic Institute (WPI) and Stanford University that uses an "obstacle course" to sort and select faster and healthier sperm cells for use in IVF treatment.
This new device was created by a team co-led by Erkan Tüzel, associate professor of physics, biomedical engineering, and computer science at WPI, and Utkan Demirci, professor of radiology and electrical engineering (by courtesy) at Stanford University. The work was funded by two separate but collaborative grants from the National Science Foundation and was published in the most recent issue of Advanced Science, a high-impact, peer-reviewed scientific journal.
The microfluidic device, which can be used in clinics, is dubbed SPARTAN, short for Simple Periodic ARray for Trapping And IsolatioN. It uses a field of three-dimensional posts that create an obstacle course for the swimming sperm cells. The strongest and healthiest sperm get through this array the fastest and then are collected at the outlet to be used in the IVF process.
Traditional sperm-sorting methods used in IVF treatments select sperm that are the fastest swimmers. The SPARTAN device collects sperm that are the fastest and also the healthiest because it culls out those with malformations, such as bent necks or larger heads, which can slow their movement..."
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This new device was created by a team co-led by Erkan Tüzel, associate professor of physics, biomedical engineering, and computer science at WPI, and Utkan Demirci, professor of radiology and electrical engineering (by courtesy) at Stanford University. The work was funded by two separate but collaborative grants from the National Science Foundation and was published in the most recent issue of Advanced Science, a high-impact, peer-reviewed scientific journal.
The microfluidic device, which can be used in clinics, is dubbed SPARTAN, short for Simple Periodic ARray for Trapping And IsolatioN. It uses a field of three-dimensional posts that create an obstacle course for the swimming sperm cells. The strongest and healthiest sperm get through this array the fastest and then are collected at the outlet to be used in the IVF process.
Traditional sperm-sorting methods used in IVF treatments select sperm that are the fastest swimmers. The SPARTAN device collects sperm that are the fastest and also the healthiest because it culls out those with malformations, such as bent necks or larger heads, which can slow their movement..."
Learn more:
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