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| thinglink.com |
"University of Illinois researchers have developed a way to produce 3-D images of live embryos in cattle that could help determine embryo viability before in vitro fertilization in humans.
Infertility can be devastating for those who want children. Many seek treatment, and the cost of a single IVF cycle can be $20,000, making it desirable to succeed in as few attempts as possible. Advanced knowledge regarding the health of embryos could help physicians select those that are most likely to lead to successful pregnancies.
The new method, published in the journal Nature Communications, brought together electrical and computer engineering professor Gabriel Popescu and animal sciences professor Matthew Wheeler in a collaborative project through the Beckman Institute for Advanced Science and Technology at the U. of I.
Called gradient light interference microscopy, the method solves a challenge that other methods have struggled with -- imaging thick, multicellular samples.
In many forms of traditional biomedical microscopy, light is shined through very thin slices of tissue to produce an image. Other methods use chemical or physical markers that allow the operator to find the specific object they are looking for within a thick sample, but those markers can be toxic to living tissue, Popescu said..."
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