Monday, December 5, 2016

Long-term use of postmenopausal estrogen treatment may impair kidney function

postmenopausal estrogen treatment and kidney function
scienceblog.com
"Long-term estrogen treatment after menopause may increase the risk of new kidney damage and negatively affect women with abnormal kidney function. New research published in the American Journal of Physiology -- Renal Physiology finds that markers for kidney damage worsened in a rat model of menopause as the length of estrogen treatment increased.

The harmful effect of high blood pressure on the blood vessels is one cause of kidney damage. Estrogen seems to protect against high blood pressure -- fewer premenopausal women have high blood pressure than men of the same age -- but after menopause, these benefits appear to diminish. Researchers from Tulane University in New Orleans studied a breed of rats that mimic the gender-specific blood pressure differences observed in humans to see if long-term hormone treatment negatively affects the kidneys..."

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