Tuesday, July 5, 2016

Three in four women starting fertility treatment will have a baby within five years

Source: European Society of Human Reproduction and Embryology | Summary: Three in four women starting fertility treatment will have a baby within five years, whether as a result of the treatment or following natural conception. The figures emerged from a large cohort study analysing the birth records of almost 20,000 women having fertility treatment in Denmark between 2007 and 2010. The majority of these women (57%) had their baby as a result of the treatment, but a significant proportion (14%) conceived spontaneously without treatment. More than half (57%) gave birth within two years.

"Three in four women starting fertility treatment will have a baby within five years, whether as a result of the treatment or following natural conception. The figures emerged from a large cohort study analysing the birth records of almost 20,000 women having fertility treatment in Denmark between 2007 and 2010. The majority of these women (57%) had their baby as a result of the treatment, but a significant proportion (14%) conceived spontaneously without treatment. More than half (57%) gave birth within two years.

Denmark is one of the few countries in the world where such a study can be done, with full registry records linking all fertility treatments (including intrauterine insemination) with all live births, and thus providing results sufficiently robust for real-life prognosis. Study presenter in Helsinki, Dr Sara Malchau of Copenhagen University Hospital, Hvidovre, Denmark, said that "we are now able to provide couples with a reliable, comprehensible, age-stratified long-term prognosis at start of treatment."

A total of 19,884 women were tracked in this analysis, with follow-up checked for live births at two, three and five years. Results showed that after two years 57% of women had had a baby, 46% of whom conceived by IVF when IVF was the first fertility treatment. However, 34% of the total delivered after intrauterine insemination when IUI was the first fertility treatment. 

Although total birth rates did increase cumulatively over the five year study period -- from 65% after three years to 71% after five years -- these rates did not increase following IUI when treatment was extended beyond two years (when most patients had switched to IVF). Moreover, 16.6% of women starting treatments with IUI had had a baby after five years not after the treatment but after spontaneous conception..."

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