"Successful outcomes in IVF require optimal environmental conditions for gametes and embryos throughout the entire cycle.
This can be accomplished by ensuring optimal pH and temperature in the incubators, and that the air in the operating theater and the laboratory is clean and free of VOC’s (volatile organic compounds).
An additional step is to ensure that media and contact materials used, support embryo development by being embryo safe and free from toxicity. In this blog post I will guide you through the basics for how to prevent toxicity from entering your culture system.
How can toxicity affect the culture system?
The negative effect of suboptimal or toxic media or contact materials on the human embryo has been referred to as reprotoxicity, a subject that been highlighted in many peer reviewed journal articles over the years1-9.
Clearly there is concern about toxicity with in the IVF community, the question is what is being done to detect and control those components that are negatively affecting gametes and embryos during IVF.
Do we really understand how these materials are or should be tested to ensure a safe and non-toxic culture environment?..."
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