Source: Karolinska Institutet | Summary: Depression and anxiety, and not necessarily the use of antidepressant medication, are associated with lower pregnancy and live birth rates following in vitro fertilization, according to a large register study in Sweden. The findings will be of interest to clinicians treating infertility and for women with depression or anxiety planning to undergo fertility treatment.
"Depression and anxiety, and not necessarily the use of antidepressant medication, are associated with lower pregnancy and live birth rates following in vitro fertilisation, according to a large register study from Karolinska Institutet in Sweden. The findings are published in the journal Fertility & Sterility and can be of interest to clinicians treating infertility and for women with depression or anxiety planning to undergo fertility treatment.
Treatment with antidepressants has increased both in general and among women of reproductive age in the last few decades. In particular, the use of selective serotonin re-uptake inhibitors, SSRIs, has increased. However, little is known about the effect of antidepressants on fertility and the ability to conceive.
The new study, including more than 23,000 women, is the largest so far assessing the association between depression, anxiety and antidepressants and the outcome of in vitro fertilisation, IVF. The investigators used anonymized data on all IVF procedures performed in Sweden from 2007 and onwards, extracted from the Swedish Quality Register of Assisted Reproduction.
They linked it to information on depression, anxiety and antidepressant prescription dispensations from the nationwide Swedish Patient and Prescribed Drug Registers..."
Read more here:
https://www.sciencedaily.com/releases/2016/03/160307093511.htm
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