"There's been a tsunami of genetic data about different cancers," says Krogan, a UC San Francisco professor of Cellular and Molecular Pharmacology and member of the UCSF Helen Diller Family Comprehensive Cancer Center. But despite this rising tide of knowledge, Krogan says, breakthroughs in cancer treatment have been slow to materialize.
In part, this is because all of the new data have only gone to show cancer's staggering diversity: Even a single tumor can contain a unique profile of thousands of genetic mutations, leaving researchers to puzzle out which are disease drivers and which are just along for the ride.
"The sequencers say we just need to pour more money into sequencing and the answer will become clear," Krogan says. "We say no. We're actually done. We've reached a point of saturation in terms of the information we can extract."
Instead of collecting yet more data, he argues, researchers need to look harder at the connections hidden in the data they already have..."
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http://medicalxpress.com/news/2016-02-big-cancer-hidden-genetic-weaknesses.html
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