DNA-based nanodevices for molecular medicine

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Self-assembled DNA nanostructures can be used in molecular-scale diagnostics and as smart drug-delivery vehicles.

Researchers from Aalto University have published an article in the recent Trends in Biotechnology journal. The article discusses how DNA molecules can be assembled into tailored and complex nanostructures, and further, how these structures can find uses in therapeutics and bionanotechnological applications. 

In the review article, the researchers outline the superior properties of DNA nanostructures, and how these features enable the development of efficient biological DNA-nanomachines. Moreover, these DNA nanostructures provide new applications in molecular medicine, such as novel approaches in tackling cancer. 

Tailored DNA structures could find targeted cells and release their molecular payload (drugs or antibodies) selectively into these cells..."

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